Panayiotou Surname Meaning
The Greek surname Panayiotou (Παναγιώτου) is a genitive patronymic meaning “of Panagiotis.” It derives from the personal name Panagiotis (Παναγιώτης), which comes from Panagia (Παναγία), the Greek title of the Virgin Mary meaning “All-Holy.” Panayiotou therefore originally identified someone as the child or descendant of a man named Panagiotis. This genitive patronymic structure is particularly widespread in Cyprus, although it also occurs elsewhere in the Greek-speaking world. The patronymic eventually stabilized as a hereditary family surname.
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About Greek Last Names and Surnames
Greek last names, also known as Greek surnames, reflect centuries of history, language, and tradition. This directory explores Greek surnames and meanings, covering both ancient origins and modern family names still in use today. Many Greek last name meanings are connected to occupations, geography, lineage, or personal traits, while others are influenced by classical history and mythology. Use this guide to research heritage, browse family names, and understand how Greek surnames developed over time.

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